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Updated: Jul 20, 2026

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长循环脂肪体平台使用基于水友性聚合物的表面修饰:制备,表征和生物评估

Jaroslav Turánek1, Petr Kosztyu2, Pavlína Turánek Knötigová3

  • 1ICRC International Clinical Research Center, St. Anne's University Hospital Brno, Czech Republic; Department of Immunology, Faculty of Medicine and Dentistry, Palacký University Olomouc, Olomouc, Czech Republic; Charles University Prague, Univ. Hosp. Hradec Králové, Inst. Clin. Immunol. & Allergol., Hradec Králové 50005, Czech Republic.

International journal of pharmaceutics
|July 14, 2024
PubMed
概括

基于N-(2-基) 甲基胺 (HPMA) 的共聚合物为脂质体表面修饰提供了比聚乙烯糖醇 (PEG) 更安全的替代品. 这些HPMA修饰的脂质体显示出长期改善的血液循环和降低的免疫反应,增强了它们作为先进药物递送平台的潜力.

关键词:
补充激活的激活方式药物输送系统是药物输送系统.这是一种HPMA共聚合物.长时间循环的脂质体隐蔽的脂肪体隐蔽的脂肪体

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