雄激素滥用:男性的风险和不良影响
Bonnie Grant1, Elizabeth Hyams1, Rhianna Davies1
1Section of Investigative Medicine, Imperial College London, London, UK.
Annals of the New York Academy of Sciences
|July 23, 2024
概括
滥用雄激素,包括类固醇-雄激素类固醇,造成严重的健康风险,如心血管问题和精神障碍,甚至在停止多年后. 临床医生必须识别和管理这些危害.
科学领域:
- 内分泌学 在内分泌学.
- 毒理学 毒理学 毒理学
- 男人的健康 男人的健康
背景情况:
- 雄激素,或类固醇-雄激素类固醇,越来越多地被滥用用于非医疗性能提升.
- 滥用与显著的死亡率和多系统不良影响有关,包括心血管,肝脏和精神健康问题.
- 消极的健康后果可能在戒烟后持续很长时间,并且由于黑市采购,披露往往是不情愿的.
研究的目的:
- 要总结与男性的雄激素滥用相关的不良影响和风险.
- 提高临床医生对雄激素滥用的患病率和危害的认识.
主要方法:
- 这是一个叙事评论.
- 该综述综合了有关雄激素滥用及其后果的现有文献.
主要成果:
- 滥用雄激素与增加的死亡率有关.
- 报告的不良反应包括心血管毒性,不孕不育,阴性双胞胎症,肝毒性和精神健康障碍.
- 管理物质依赖和复发的长期健康后果和挑战是重大的.
结论:
- 跨专业的临床医生需要意识到雄激素滥用,其患病率及其对男性及其家庭的有害影响.
- 副作用的管理是复杂的,需要特定器官的方法,并解决身体,神经精神和依赖问题的问题.
- 鼓励戒除雄激素滥用对于减轻长期健康风险至关重要.
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