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Updated: Jun 4, 2025

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INSIHGT:一个可访问的多规模,多模式的3D空间生物学平台

Chun Ngo Yau1,2, Jacky Tin Shing Hung1,2, Robert A A Campbell3

  • 1Department of Psychiatry, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.

Nature communications
|December 31, 2024
PubMed
概括

INSIHGT是一种新的3D空间生物学方法,可以进行深层组织探测,以进行全面的分子映射. 这种技术保留了多样化的生物分子,推进了系统生物学和多omics研究.

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Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...
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