用于脉冲氧计性能测试的基组织幻象的开发和表征
Anant Bhusal1,2, Masoud Farahmand2, Md Sadique Hasan2
1University of Massachusetts, Department of Biomedical Engineering, Amherst, Massachusetts, United States.
Journal of biomedical optics
|January 8, 2025
概括
研究人员开发出基于的手指幻象来测试脉冲氧计,解决精度差异. 这些组织模拟材料 (TMM) 允许对更公平的医疗器械进行可靠的基板性能评估.
科学领域:
- 生物医学工程 生物医学工程
- 光学传感传感器是什么?
- 材料科学 材料科学 材料科学
背景情况:
- 脉冲氧计对于患者护理至关重要,但需要对人体进行测试,并根据皮肤颜色表现出测量差异.
- 使用组织模拟幻象开发可靠的基板测试可以改善市场前评估和设备准确性.
- 定制组织模拟材料 (TMM) 对于创建模拟生理条件的现实幻影至关重要.
研究的目的:
- 开发和描述基于的新型组织模拟材料 (TMM),用于创建现实的手指幻影.
- 为了实现这些幻象在脉冲性流体网络中进行脉冲氧计性能测试.
- 评估TMM模拟生物光学和机械性能的能力,并模拟表皮黑色素含量的变化.
主要方法:
- 配制的柔性弹性体,具有不同的组件和固化协议,以实现所需的机械和光学性能.
- 开发了通道化的手指幻象,并将其集成到一个脉动式压力流体网络中.
- 采用光学连贯断层扫描 (OCT) 来测量通道直径,以及用于光学信号采集的光电图 (PPG) 传感器.
主要成果:
- 优化的TMM表现出32的Shore OO硬度和130kPa的弹性模量.
- 幻影通道直径显示了线性压力依赖的合规性,通过OCT测量.
- 该系统产生了可调节的光聚聚聚光学 (PPG) 调制水平 (0.6%18.1%在940nm) 和模拟的表皮黑色素含量变化.
结论:
- 建立了创建基于的组织幻象工具的最佳实践,用于脉冲氧计性能测试.
- 证明了这些幻象在促进脉冲氧计市场前评估方面的潜力.
- 强调TMM开发对于创造更准确,更公平的脉冲氧度仪器的重要性.
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