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Updated: Jun 22, 2026

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预训练深度神经网络Kin-SiM用于单分子FRET痕迹理想化

Leyou Zhang1, Jieming Li2, Nils G Walter3

  • 1Google, New York City, New York 10011, United States.

The journal of physical chemistry. B
|January 14, 2025
PubMed
概括

本研究介绍了Kin-SiM,这是一种使用长短期记忆 (LSTM) 网络的深度学习方法,用于自动化单分子光共振能量转移 (smFRET) 数据分析. Kin-SiM准确地识别了生物分子状态和动态,减少了smFRET研究中的手工努力和偏差.

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Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...