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Updated: Jul 18, 2026

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非侵入性植入前遗传检测:使用等离子生物传感器在胚胎培养基中检测无细胞DNA

Noemi Bellassai1,2, Anil Biricik3, Matteo Surdo3

  • 1Department of Chemical Sciences, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy.

Analytical chemistry
|August 28, 2025
PubMed
概括

这项研究引入了一种用于胚胎遗传查的新型非侵入性植入前遗传检测 (niPGT) 方法. 这种先进的生物传感器可以检测无细胞DNA中的单点突变,从而改善体外受精 (IVF) 的胚胎选择.

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In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.