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基于移动应用程序的干预和心血管风险因素在2型糖尿病患者:随机临床试验

Pei-Zhen Zhang1, Dan Guo1, Chang-Qin Liu2

  • 1Department of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University, Guangzhou, China.

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概括

在患有2型糖尿病 (T2D) 和心血管疾病风险因素的成年人中,手机短信适度改善了血糖控制和降低了缩血压. 这种干预提供了管理T2D及其并发症的潜在策略.

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科学领域:

  • 心脏病学
  • 内分泌学
  • 数字健康

背景情况:

  • 对2型糖尿病 (T2D) 患者来说,控制可改变的心血管风险因素至关重要,但仍未得到充分利用.
  • 基于移动信息的干预措施有望解决这一差距,但需要更多证据证明它们对多种风险因素的有效性.

研究的目的:

  • 评估基于移动信息的干预措施对T2D患者心血管风险因素的有效性.
  • 评估干预对血糖控制 (HbA1c),低密度脂蛋白胆固醇 (LDL-C) 和静脉血压 (SBP) 的影响.

主要方法:

  • 一项随机临床试验,涉及中国未控制的T2D和心血管疾病 (CVD) 风险因素的成年人.
  • 参与者接受了通常的护理或为期12个月的干预,每周发送6条以改变血糖控制和心血管疾病风险管理为重点的短信.
  • 主要结局包括HbA1c,LDL- C和SBP的变化;次要结局包括受控的HbA1c水平. 使用治疗意向原则分析了数据.

主要成果:

  • 与基线相比,干预组的HbA1c (-2. 8%) 和SBP (-2. 5 mm Hg) 显著降低.
  • 虽然LDL- C也下降,但组间的净差异没有统计学意义.
  • 干预组中更高的参与者达到控制的HbA1c水平 (54. 0%对46. 1%).

结论:

  • 基于移动信息的干预措施对T2D和心血管疾病风险因素的成年人产生了适度的HbA1c和SBP改善.
  • 这些发现支持考虑移动消息策略,以加强T2D患者的血糖控制和心血管疾病风险管理.