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Updated: May 8, 2026

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通过微流体控制自动化,为生命科学推进多重,稳定和短暂流量的开源

Junichi Murai1,2, Mahmoud N Abdelmoez1,3, Keisuke Kondo1,2

  • 1Institute for Life and Medical Sciences, Kyoto University, Japan. shintaku@infront.kyoto-u.ac.jp.

Lab on a chip
|September 3, 2025
PubMed
概括

我们开发了微流体序列自动化 (MiSA), MiSA可以实现多重应用,如测序和滴滴生成,具有高度的灵活性和可靠性.

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In aerobic fermentations, oxygen is vital for microbial growth and metabolite production. Since air comprises only about 20% oxygen and the gas is poorly soluble in water—just 9 ppm at 20°C—supplying sufficient oxygen becomes a critical challenge, especially in high-demand processes like yeast growth or citric acid production. Even a fully saturated broth may offer only a few seconds of oxygen availability.To address this, sterile or scrubbed air is introduced into the fermentor via a sparger...