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Updated: Jul 2, 2026

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
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凝珠颗粒能够基于活动识别核酸aptamer酶抑制剂的核酸抑制剂.

Amanda A Nguyen1, Brian M Paegel1,2

  • 1Department of Pharmaceutical Sciences, University of California, Irvine, California 92697, United States.

Analytical chemistry
|September 15, 2025
PubMed
概括

我们开发了一种新的阿普坦体查系统,它利用酶活性来识别功能性核酸阿普坦体. 这种方法通过选择结合和功能来增强胺体的发现,提高了选择效率.

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相关概念视频

Enzyme Inhibition01:30

Enzyme Inhibition

Inhibitors are molecules that reduce enzyme activity by binding to the enzyme. In a normally functioning cell, enzymes are regulated by a variety of inhibitors. Drugs and other toxins can also inhibit enzymes. Some inhibitors bind to the enzyme’s active site, while others inhibit enzymatic activity by binding to other sites on the protein structure.