执行功能测试表现与治疗结果之间的关系 在治疗晚年抑郁症的简短心理治疗期间
Matthew S Schurr1, Yiqun T Chen1, Patrick J Raue1
1Department of Psychology (MSS, BNR), University of Nevada, Las Vegas, NV; Department of Psychiatry (MSS), McLean Hospital, Belmont, MA; Data Science Institute and Department of Biomedical Data Science (YTC), Stanford University, Stanford, CA; Department of Psychiatry and Behavioral Sciences (PJR, PAA), University of Washington, Seattle, WA; and the Weill Cornell Institute of Geriatric Psychiatry (GSA), Weill Cornell Medicine, White Plains, NY.
概括
执行功能没有预测老年人抑郁症症状的改善. 然而,简短的心理治疗改善了与决策和执行功能相关的认知测试.
科学领域:
- 老年精神病学是一门精神病学专业.
- 神经心理学 神经心理学
- 临床心理学 临床心理学
背景情况:
- 执行功能障碍是晚年抑郁症 (LLD) 的常见挑战.
- 了解执行功能与治疗结果之间的关系对于LLD至关重要.
- 简短的心理治疗越来越多地用于老年人的抑郁症.
研究的目的:
- 为了确定执行功能是否预测短暂的心理治疗期间抑郁症状的变化.
- 评估在LLD心理治疗期间认知测试表现是否有所改善.
主要方法:
- 对一项随机临床试验的后期分析,比较解决问题疗法 (PST) 和Engage.
- 150名患有严重抑郁症的老年人 (60-89岁) 参与了这项研究.
- 在治疗前和治疗后进行认知测试 (IGT,WCST,Stroop,Digit Span,HVLT-R) 和抑郁度量表 (HAM-D,WHODAS).
主要成果:
- 基线执行功能没有预测汉密尔顿抑郁评分表 (HAM-D) 评分的改善.
- 在Stroop测试中的更好的表现与改善的世界卫生组织残疾评估计划 (WHODAS) 成绩相关.
- 在治疗9周后,爱荷华州博任务 (IGT) 和Stroop测试的表现有显著改善.
结论:
- 基线执行功能似乎没有影响LLD中抑郁症状的减少.
- 简短的心理治疗可以增强执行功能的特定方面,例如基于奖励的决策.
- 这些发现表明,在LLD治疗中,在症状缓解的同时,可以出现认知改善.
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