多功能rGO/Y2O3@hydroxyapatite生物陶:结构,光学和生物医学特性
Elbadawy A Kamoun1, Asmaa Elawadly2, Merna H Emam3
1Department of Chemistry, College of Science, King Faisal University Al-Ahsa 31982 Saudi Arabia ekamoun@kfu.edu.sa badawykamoun@yahoo.com +201283320302.
RSC advances
|January 26, 2026
概括
氧化 (HAp) / 减少的氧化石烯 (rGO) / 氧化 (Y2O3) 复合物为骨再生和癌症治疗提供双重功能. 这些新型生物陶显示了增强的光学特性和显著的抗菌活性,为先进的生物医学应用铺平了道路.
科学领域:
- 生物材料科学 生物材料科学
- 纳米技术 纳米技术
- 材料化学 材料化学
背景情况:
- 酸 (HAp) 是骨组织工程中的一个关键组成部分.
- 减少的石墨烯氧化物 (rGO) 和氧化物 (Y2O3) 可以赋予生物材料新特性.
- 需要多功能材料,用于结合骨再生和癌症治疗.
研究的目的:
- 为了合成和表征HAp/rGO/Y2O3复合材料,用于双重应用.
- 通过将rGO和Y2O3.3结合起来,研究HAp的结构,光学和功能增强.
- 评估这些复合材料在骨再生和癌症治疗中的潜力.
主要方法:
- 复合材料使用乙醇辅助湿混合制备,然后干燥和热处理.
- 使用XRD,FT-IR,SEM和UV/Vis光谱分析了结构和光学特性.
- 评估了抗菌活性,细胞毒性 (MTT测定) 和生物膜减少.
主要成果:
- XRD证实了相纯度,FT-IR验证了功能组相互作用.
- SEM显示了密集的,均的形态与减少的粒子大小 (~380 nm).
- 光学带隙从5.42 eV (HAp) 缩小到4.73 eV (复合材料),增强了光吸收.
- 观察到显著的生物膜减少 (>90%) 对格拉姆阳性细菌.
- 细胞毒性研究显示大多数复合材料的高CC50值 (>100μg mL-1),表明安全性.
- 复合材料显示出对协同抗癌活性和骨质导电性的潜力.
结论:
- HAp/rGO/Y2O3复合材料表现出增强的物理化学和光学性能.
- 这些纳米复合材料显示出作为骨愈合和局部癌症治疗的双重功能材料的前景.
- 开发的材料适用于集成骨再生和向癌症治疗平台.
相关概念视频
02:24Properties of Enantiomers and Optical Activity
21.5K
It is essential to understand the difference between chiral and achiral interactions and the implications thereof in optical activity and their applications. Just as our feet, which are chiral, interact uniquely with chiral objects, such as a pair of shoes, but identically with achiral socks, enantiomers of a molecule exhibit different properties only when they interact with other chiral media. An example of a significant implication from this facet is the phenomenon known as optical activity,...
21.5K
01:21Structural Properties and Dimensions of Lumber
394
Wood's structural properties derive from fibers aligned along the tree's length, contributing significantly to its mechanical strength. Wood exhibits up to twenty times greater tensile strength along these fibers compared to across them, and generally shows better performance under compression than tension. The length of fibers varies, with hardwoods having fibers around one twenty-fifth inch long and softwoods ranging from one-eighth to one-third inch.
The strength characteristics of...
The strength characteristics of...
394
02:37Structure and Physical Properties of Alkynes
13.1K
Introduction:
In nature, compounds containing both carbon and hydrogen are known as "hydrocarbons". Aliphatic hydrocarbons are compounds whose molecules contain saturated single bonds (i.e., alkanes) or unsaturated double or triple bonds. Alkenes contain carbon–carbon double bonds and have a structural formula CnH2n. Unsaturated hydrocarbons containing carbon–carbon triple bonds are called "alkynes" and are structurally represented by the formula CnH2n-2.
The...
In nature, compounds containing both carbon and hydrogen are known as "hydrocarbons". Aliphatic hydrocarbons are compounds whose molecules contain saturated single bonds (i.e., alkanes) or unsaturated double or triple bonds. Alkenes contain carbon–carbon double bonds and have a structural formula CnH2n. Unsaturated hydrocarbons containing carbon–carbon triple bonds are called "alkynes" and are structurally represented by the formula CnH2n-2.
The...
13.1K
02:34Structural Isomerism
21.5K
Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula. Structural isomerism of coordination compounds can be divided into two subcategories, the linkage isomers and coordination-sphere isomers.
Linkage isomers occur when the coordination compound contains a ligand that can bind to the transition metal center through two different atoms. For example, the CN− ligand can bind through the carbon atom or through the nitrogen atom. Similarly, SCN− can...
Isomers are different chemical species that have the same chemical formula. Structural isomerism of coordination compounds can be divided into two subcategories, the linkage isomers and coordination-sphere isomers.
Linkage isomers occur when the coordination compound contains a ligand that can bind to the transition metal center through two different atoms. For example, the CN− ligand can bind through the carbon atom or through the nitrogen atom. Similarly, SCN− can...
21.5K
02:57Physical and Chemical Properties of Matter
165.8K
The characteristics that enable us to distinguish one substance from another are called properties.
165.8K
02:58Properties of Transition Metals
29.7K
Transition metals are defined as those elements that have partially filled d orbitals. As shown in Figure 1, the d-block elements in groups 3–12 are transition elements. The f-block elements, also called inner transition metals (the lanthanides and actinides), also meet this criterion because the d orbital is partially occupied before the f orbitals.
29.7K