使iESCC

Yu Zhang1, Li-Hua Liu2, Shuqi Wang2

  • 1Biosciences Central Research Facility, The Hong Kong University of Science and Technology, GuangZhou 510000, China.

Bioresource technology
|January 27, 2026
PubMed
概括

一个新的深度学习模型,iESC,从酶序列和基质结构准确地预测了诸如迈凯利斯常数 (Km) 和循环数 (kcat) 等酶动态参数,加速了酶研究.

相关概念视频

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Sensitivity, Specificity, and Predicted Value

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Constant Pressure Calorimetry03:02

Constant Pressure Calorimetry

Calorimetry is a technique used to measure the amount of heat involved in a chemical or physical process or to measure the heat transferred to or from a substance. The heat is exchanged with a calibrated and insulated device called the calorimeter. Calorimetry experiments are based on the assumption that there is no heat exchange between the insulated calorimeter and the external environment. The well-insulated calorimeters prevent the transfer of heat between the calorimeter and its external...
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Enzymes02:34

Enzymes

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Constant Volume Calorimetry02:41

Constant Volume Calorimetry

Calorimeters are useful to determine the heat released or absorbed by a chemical reaction. Coffee cup calorimeters are designed to operate at constant (atmospheric) pressure and are convenient to measure heat flow (or enthalpy change) accompanying processes that occur in solution at constant pressure. A different type of calorimeter that operates at constant volume, colloquially known as a bomb calorimeter, is used to measure the energy produced by reactions that yield large amounts of heat and...
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Calculating the Equilibrium Constant02:46

Calculating the Equilibrium Constant

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Enzyme Kinetics

Enzymes speed up reactions by lowering the activation energy of the reactants. The speed at which the enzyme turns reactants into products is called the rate of reaction. Several factors impact the rate of reaction, including the number of available reactants. Enzyme kinetics is the study of how an enzyme changes the rate of a reaction.
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