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Updated: Feb 13, 2026

In vitro Induction of Human Dental Pulp Stem Cells Toward Pancreatic Lineages
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对于正确的牙形成和干细胞调节,Sfrp4是必需的

G Sarra1, S Parsaei1, M P Gomes1

  • 1Division of Bone and Mineral Research, Department of Oral Medicine Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, USA.

Journal of dental research
|February 11, 2026
PubMed
概括

泄露的纹相关蛋白4 (SFRP4) 损失导致皮尔病并影响牙发育. 在小鼠中,SFRP4 缺乏会导致切口较短和牙,影响干细胞的维持和牙的生长.

关键词:
没有信号通道.艾美洛布拉斯特细胞的发生.牙的生长过程刺刀 刺刀是指刺刀的使用者.皮尔氏病是皮尔氏病的一种疾病.干细胞是干细胞的组成部分.

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