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综合的甲基组-转录组分析揭示了表观基因组重塑和Rho GTPase相关的免疫-上皮层交叉点在亚托皮性皮肤炎中

Tiina Skoog1, Ying Yang2,3, Peter Olah4,5

  • 1Department of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden.

Allergy
|February 18, 2026
PubMed
概括

皮肤上的表观遗传学变化,包括DNA甲基化,至关重要. 这项研究整合了多omics数据,揭示了Rho GTPase信号作为AD病变发生的关键调节器.

关键词:
亚托邦性皮肤炎的发生.甲基组学 甲基组学微生物群的生物失调症 (microbiome dysbiosis) 是一种疾病.翻译学 翻译学 翻译学 翻译学

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