长期COVID-19嗅觉功能障碍:心理物理测试与自我感知之间的差异
Aina Sansa1, Alda Cardesín1, Mariana Campos1
1Hospital Parc Taulí, Otorhinolaryngology Department, Rhinology and Sleep Unit, Sabadell, Spain.
Brazilian journal of otorhinolaryngology
|March 10, 2026
概括
长期COVID-19患者表现出嗅觉识别缺陷,这些缺陷在主观测试中没有得到反映. 这种嗅觉功能障碍与其他鼻子疾病不同,需要量身定制的诊断和治疗方法.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经学 神经学
- 传染性疾病 传染性疾病
背景情况:
- 嗅觉功能障碍是COVID-19的一个常见的后果.
- 长期COVID-19患者经常报告持续的气味和味觉障碍.
- 了解嗅觉障碍的性质对于有效管理至关重要.
研究的目的:
- 为了比较客观的嗅觉测试结果与长期COVID-19患者的主观嗅觉感知.
- 描述长期的COVID-19嗅觉功能障碍,并将其与具有鼻息肉 (CRSwNP) 的慢性鼻炎进行比较.
- 为制定有针对性的诊断和治疗策略提供信息.
主要方法:
- 一项涉及86名长期COVID-19患者的观察性研究.
- 使用巴塞罗那嗅觉测试 (BAST-24 Plus),视觉模拟量表 (VAS) 和中鼻结局测试 (SNOT-22) 的评估.
- 与120名健康对照和121名CRSwNP患者进行了比较.
主要成果:
- 与对照组相比,长期COVID-19患者在气味检测和识别方面表现出显著的缺陷.
- 长期COVID-19中的嗅觉障碍不如CRSwNP中那么严重.
- 主观嗅觉 (VAS) 与气味识别的相关性比检测更强,但总体而言,主观感知与客观测试成绩的相关性并不好.
结论:
- 长期COVID-19患者的主观嗅觉感知与客观心理物理测试结果不一致.
- 长期COVID-19嗅觉功能障碍主要表现为识别障碍,与其他鼻子疾病中发现的检测主导障碍不同.
- 长期的COVID-19嗅觉功能障碍需要特定的诊断工具和治疗策略.
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