Related Experiment Video
Updated: Aug 13, 2026

Analysis of LINE-1 Retrotransposition at the Single Nucleus Level
Published on: April 23, 2016
Revising the selfish DNA hypothesis: new evidence on accumulation of transposable elements in heterochromatin
1Dipartimento di Genetica e Biologia Molecolare, Università 'La Sapienza', Piazzale A. Moro, 00185 Roma, Italy. dmitri@axcasp.caspur.it
Abstract:
The bulk of the eukaryotic genome is composed of families of repetitive sequences that are genetically silent and exhibit various types of instability. Transposable elements (TEs) are particularly common in heterochromatic regions of the genome - a location where TEs might do less damage to their host. Recent advances suggest that the relationship between TEs and heterochromatin might not be quite so straightforward.
Related Concept Videos
Position-effect Variegation
Overview of Transposition and Recombination
DNA-only Transposons
The donor site from where the transposon is excised is either degraded or...
Non-LTR Retrotransposons
Heterochromatin
Constitutive heterochromatin: It is a highly compact region of chromatin that is mostly concentrated in the centromere and telomere. Unlike euchromatin, the amino acid at 9th...
Heterochromatin
Constitutive heterochromatin: It is a highly compact region of chromatin that is mostly concentrated in the centromere and telomere. Unlike euchromatin, the amino acid at 9th...

