Related Experiment Videos
Systemic replacement therapy from genetically modified epidermal keratinocytes
1Department of Dermatology and Oral Biology and Pathology, State University of New York at Stony Brook, NY 11794-8702, USA.
Abstract:
Epidermal keratinocytes are a potential vehicle for gene transfer and systemic delivery. We review data showing that epidermis-secreted protein does indeed reach the circulation, and we discuss factors that bear upon the issue of how much protein epidermal keratinocytes can deliver to the circulation.