Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antioxidants and exercise.

S K Powers1, K Hamilton

  • 1Department of Exercise and Sport Sciences, University of Florida, Gainesville, USA. spowers@hhp.ufl.edu

Clinics in Sports Medicine
|July 20, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The collaborative working group method for pre-trial knowledge mobilisation: a qualitative evaluation of a structured process for iteratively refining a complex intervention (DAFNEplus).

Pilot and feasibility studies·2024
Same author

A qualitative investigation of individuals' lay representations of habit.

Psychology & health·2024
Same author

Deeply Virtual Compton Scattering Cross Section at High Bjorken x_{B}.

Physical review letters·2022
Same author

Form Factors and Two-Photon Exchange in High-Energy Elastic Electron-Proton Scattering.

Physical review letters·2022
Same author

First test of the theory of reasoned goal pursuit: predicting physical activity.

Psychology & health·2022
Same author

Deep Exclusive Electroproduction of π^{0} at High Q^{2} in the Quark Valence Regime.

Physical review letters·2021
Same journal

"Women's Sports Is Still in its Infancy." - Billie Jean King.

Clinics in sports medicine·2026
Same journal

Treatment Considerations in the Female Athlete.

Clinics in sports medicine·2026
Same journal

Sports Considerations Related to Pregnancy and Postpartum.

Clinics in sports medicine·2026
Same journal

Management of Bone Stress Injuries: A Holistic Approach.

Clinics in sports medicine·2026
Same journal

Relative Energy Deficiency in Sport.

Clinics in sports medicine·2026
Same journal

Gymnastics-Related Injuries for the Female Athlete.

Clinics in sports medicine·2026
See all related articles

Exercise increases reactive oxygen species (ROS), potentially causing muscle fatigue. While antioxidants combat oxidative stress in cells, dietary supplements show limited benefits for human exercise performance, warranting further research.

Area of Science:

  • Exercise physiology
  • Biochemistry
  • Cellular biology

Background:

  • Muscular exercise elevates reactive oxygen species (ROS) production.
  • Cytotoxic ROS are implicated in exercise-induced muscle redox disturbances, potentially leading to fatigue or injury.
  • Muscle cells possess enzymatic and nonenzymatic antioxidant defense systems.

Purpose of the Study:

  • To review the role of reactive oxygen species (ROS) in exercise-induced muscle damage.
  • To summarize the endogenous antioxidant defense mechanisms in muscle cells.
  • To evaluate the efficacy of antioxidant supplementation on human exercise performance.

Main Methods:

  • Literature review of studies on exercise, oxidative stress, and antioxidants.
  • Analysis of endogenous antioxidant systems (enzymatic and nonenzymatic).

Related Experiment Videos

  • Examination of evidence for antioxidant supplementation in human performance studies.

    • Main Results:

    • Exercise generates ROS, impacting muscle redox balance.
    • Key antioxidant enzymes include superoxide dismutase, glutathione peroxidase, and catalase.
    • Nonenzymatic antioxidants include vitamins E and C, beta-carotene, and glutathione.
    • Animal studies suggest performance benefits from antioxidants, but human data is limited.

    Conclusions:

    • Muscle cells have robust antioxidant defenses against exercise-induced oxidative stress.
    • Current evidence does not strongly support antioxidant supplementation for improving human exercise performance.
    • Further research is needed to clarify the role of antioxidants in human athletic performance.