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An economical synthesis of famciclovir
T Hijiya1, K Yamashita, M Kojima
1AminoScience Laboratories, Ajinomoto Co. Inc., Kawasaki, Japan.
Abstract:
An economical synthesis of famciclovir from N-2-acetyl-7-benzylguanine by a novel regioselective alkylation with the diester cyclopropane compound was developed.
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