Related Experiment Videos
Synthesis and biophysical studies of modified oligonucleotides containing acyclic amino alcohol nucleoside analogs
K S Ramasamy1, V Stoisavljevic
1Research Division, ICN Pharmaceuticals, Inc., Costa Mesa, CA 92626, USA.
Abstract:
Novel serine derivative of thymine was prepared and incorporated into oligonucleotides. These modified oligonucleotides were studied for their binding affinity with complementary DNA/RNA.