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[Hepatitis C virus-associated dermatoses: a review].

S Krengel1, B Tebbe, S Goerdt

  • 1Klinik und Poliklinik für Dermatologie, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|September 29, 1999
PubMed
Summary

Hepatitis C virus (HCV) infection often presents without symptoms but can lead to chronic skin conditions. This review details common and rare dermatologic disorders linked to HCV, including lichen planus and vasculitis.

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Area of Science:

  • Dermatology
  • Hepatology
  • Virology

Context:

  • Hepatitis C virus (HCV) infection can manifest with various dermatological conditions during its chronic phase.
  • Several common skin diseases, including lichen planus, cryoglobulinemic vasculitis, and porphyria cutanea tarda, are known to be associated with HCV.
  • Less common dermatologic disorders have also been reported in conjunction with HCV-induced liver disease.

Purpose:

  • To summarize recent literature on the association between Hepatitis C virus infection and dermatologic disorders.
  • To present three case studies observed by the authors.
  • To provide an updated overview of this topic.

Summary:

  • Acute Hepatitis C virus (HCV) infection is frequently asymptomatic but can lead to chronic conditions affecting multiple organ systems.

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  • Common dermatological conditions associated with HCV include lichen planus, cryoglobulinemic vasculitis, and porphyria cutanea tarda.
  • Other reported dermatologic manifestations linked to HCV-induced liver disease include psoriasis, chronic urticaria, pruritus, pseudo-Kaposi sarcoma, necrolytic migratory erythema, and Behçet disease.
  • Impact:

    • Highlights the significant impact of Hepatitis C virus on dermatological health.
    • Emphasizes the need for dermatologists to consider HCV in patients presenting with specific skin conditions.
    • Contributes to a better understanding and updated knowledge base for managing HCV-associated dermatoses.