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[Hepatitis C virus-associated dermatoses: a review]

S Krengel1, B Tebbe, S Goerdt

  • 1Klinik und Poliklinik für Dermatologie, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|September 29, 1999
PubMed

Insights

Hepatitis C virus (HCV) infection often presents without symptoms but can lead to chronic skin conditions. This review details common and rare dermatologic disorders linked to HCV, including lichen planus and vasculitis.

Area of Science:

  • Dermatology
  • Hepatology
  • Virology

Context:

  • Hepatitis C virus (HCV) infection can manifest with various dermatological conditions during its chronic phase.
  • Several common skin diseases, including lichen planus, cryoglobulinemic vasculitis, and porphyria cutanea tarda, are known to be associated with HCV.
  • Less common dermatologic disorders have also been reported in conjunction with HCV-induced liver disease.

Purpose:

  • To summarize recent literature on the association between Hepatitis C virus infection and dermatologic disorders.
  • To present three case studies observed by the authors.
  • To provide an updated overview of this topic.

Summary:

  • Acute Hepatitis C virus (HCV) infection is frequently asymptomatic but can lead to chronic conditions affecting multiple organ systems.
  • Common dermatological conditions associated with HCV include lichen planus, cryoglobulinemic vasculitis, and porphyria cutanea tarda.
  • Other reported dermatologic manifestations linked to HCV-induced liver disease include psoriasis, chronic urticaria, pruritus, pseudo-Kaposi sarcoma, necrolytic migratory erythema, and Behçet disease.

Impact:

  • Highlights the significant impact of Hepatitis C virus on dermatological health.
  • Emphasizes the need for dermatologists to consider HCV in patients presenting with specific skin conditions.
  • Contributes to a better understanding and updated knowledge base for managing HCV-associated dermatoses.

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