A kinetics study on the production of alkaline proteinase by Bacillus licheniformis 2709

With automatic control fermentation equipment, the kinetics of growth and metabolism of Bacillus licheniformis 2709 was studied with batch culture as well as with fed-batch-culture by controlling the concentration of the growth-limiting substrate. The Monod formula proved to be reasonable in describing the relationship between cell growth rate of B. licheniformis 2709 and the concentration of the growth-limiting substrate in the broth, and the data of product synthesis rate showed that the fermentation type belongs to one partially related to growth.