Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Phototherapy].

A Wirz-Justice1, P Graw

  • 1Abteilung Chronobiologie, Psychiatrische Universitätsklinik Basel.

Therapeutische Umschau. Revue Therapeutique
|March 24, 2000
PubMed
Summary
This summary is machine-generated.

Seasonal Affective Disorder (SAD) affects 2% of European adults, primarily women. Light therapy is a first-line treatment, with effects often seen within a week.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Chronobiology comes of age.

Acta psychiatrica Scandinavica·2017
Same author

Circadian rhythms and sleep regulation in seasonal affective disorder.

Acta neuropsychiatrica·2016
Same author

Challenging the sleep homeostat: sleep in depression is not premature aging.

Sleep medicine·2012
Same author

[Depression during pregnancy and its treatment].

Der Nervenarzt·2009
Same author

Mood elevation and pituitary stimulation after i.v. l-5-HTP in normal subjects: Evidence for a common serotoninergic mechanism.

Neuroscience letters·2009
Same author

Annual rhythm of serum melatonin in man.

Neuroscience letters·2009
Same journal

[Multimodal Cardiac Imaging: New Developments for Clinical Practice].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Coronary angiography: From cardiac catheterization to advanced interventional cardiovascular imaging].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Athlete's heart: role of cardiac imaging in the prevention of sudden cardiac death].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Multimodal imaging in cardiac amyloidosis and cardiac sarcoidosis].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Inflammatory Heart Disease: The Role of Multimodality Cardiac Imaging in Myocarditis and Pericarditis].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

State-of-the-Art Cardiac Imaging

Therapeutische Umschau. Revue therapeutique·2026
See all related articles

Area of Science:

  • Psychiatry
  • Chronobiology
  • Light Therapy Research

Context:

  • Seasonal Affective Disorder (SAD) is a mood disorder characterized by recurrent depressive episodes linked to seasonal changes, affecting approximately 2% of the European adult population.
  • The condition exhibits a significant female predominance, with a 4:1 female to male ratio.
  • Diagnosis involves identifying recurrent major depressive episodes that occur during winter months and remit in summer.

Purpose:

  • To outline recommendations for light therapy as a primary treatment for Seasonal Affective Disorder (SAD).
  • To detail optimal parameters for light therapy, including dosage, duration, and timing.
  • To discuss adjunctive treatments and potential applications for other psychiatric conditions.

Summary:

Related Experiment Videos

  • Light therapy is recommended as the first-line treatment for SAD, with specific dosages based on light intensity (e.g., 10,000 lux for 30 minutes/day or 2,500 lux for 1-2 hours/day).
  • Optimal timing for light therapy is in the morning shortly after awakening, though flexibility is advised for consistent practice.
  • Antidepressant effects can manifest rapidly, often within one week, with stable results typically achieved after 2-4 weeks of consistent treatment. For non-responders, combining light therapy with Selective Serotonin Reuptake Inhibitors (SSRIs) is suggested.
  • Impact:

    • Light therapy offers a safe and effective first-line treatment for SAD, with rare side effects that can be managed by adjusting light dosage.
    • Ophthalmological risks are minimal under normal conditions, but individuals with pre-existing retinal conditions or on photosensitizing medications should seek professional examination.
    • Preliminary evidence suggests light therapy's potential as an adjuvant treatment for other conditions with seasonal patterns, including premenstrual dysphoric disorder and non-seasonal depression.