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7-Caffeoylsedoheptulose from Nyssa sylvatica.

X C Li1, H N elSohly, A M Clark

  • 1National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, USA.

Phytochemistry
|May 23, 2000
PubMed
Summary
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A novel compound, 7-Caffeoylsedoheptulose, was identified in Black Tupelo wood. This discovery adds to the known phytochemicals from this plant species.

Area of Science:

  • Phytochemistry
  • Natural Product Chemistry
  • Botany

Background:

  • Nyssa sylvatica (Black Tupelo) is a tree species with a history of traditional medicinal uses.
  • The chemical constituents of Nyssa sylvatica have not been fully elucidated.
  • Understanding plant-derived compounds is crucial for potential pharmaceutical applications.

Purpose of the Study:

  • To isolate and identify novel chemical compounds from the wood of Nyssa sylvatica.
  • To characterize the structure of the isolated compounds using spectroscopic and chemical methods.

Main Methods:

  • Extraction of compounds from Nyssa sylvatica wood.
  • Purification using chromatographic techniques.
  • Structure elucidation via Nuclear Magnetic Resonance (NMR) spectroscopy, Mass Spectrometry (MS), and chemical derivatization.

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Main Results:

  • Isolation of 7-Caffeoylsedoheptulose, a previously undescribed compound.
  • Identification of two ellagic acid derivatives and scopoletin.
  • Confirmation of the structure of 7-Caffeoylsedoheptulose through comprehensive spectral and chemical analyses.

Conclusions:

  • 7-Caffeoylsedoheptulose is a newly identified phytochemical from Nyssa sylvatica.
  • The findings expand the known phytochemical profile of Black Tupelo.
  • This research contributes to the understanding of natural product diversity in medicinal plants.