Related Experiment Video
Updated: Jul 20, 2026

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness
Published on: May 2, 2017
Practical nutritional management in the trauma intensive care unit.
1Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, USA. pdabrows@mail.med.upenn.edu
Critically injured patients require specialized nutritional support to combat hypermetabolism and catabolism. Early and appropriate nutrition can reduce complications and improve outcomes for these complex cases.
Area of Science:
- Critical care medicine
- Trauma surgery
- Intensive care unit (ICU) management
Background:
- Critically injured patients present complex physiological challenges due to trauma, shock, or sepsis.
- These conditions trigger a hypermetabolic, catabolic state that disrupts nutritional homeostasis.
- Pre-existing conditions further complicate the management of these patients.
Purpose of the Study:
- To outline a practical approach to nutritional support for critically injured patients.
- To highlight the importance of appropriate nutritional interventions in managing hypermetabolism.
- To discuss the potential benefits of nutritional support in reducing complications.
Main Methods:
- Review of existing studies on feeding routes, substrates, and timing of nutritional support.
- Emphasis on a practical, individualized approach to patient care.
- Consideration of the heterogeneous nature of critically injured patient populations.
Main Results:
- Nutritional support can minimize the catabolic effects of critical illness.
- Adequate nutritional intervention may decrease infectious complications.
- Optimizing nutritional support can modulate the metabolic response to injury.
Conclusions:
- Severely injured patients often require directed nutritional support due to inability to eat conventionally.
- A practical, evidence-based approach is crucial for effective nutritional management.
- Tailored nutritional strategies are essential for improving outcomes in critical care settings.
Related Concept Videos
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Acute Kidney Injury V: Interprofessional Care
Acute Kidney Injury VI: Nursing Management
Chronic Kidney Disease III: Interprofessional Care
