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Published on: May 6, 2014
Rational treatment of empyema in children
A H Meier1, B Smith, A Raghavan
1Division of Pediatric Surgery, Stanford University, 725 Welch Rd, Palo Alto, CA 94304, USA.
Pediatric empyema treatment is effective and cost-efficient using thoracostomy tube drainage (TTD) with or without fibrinolytic therapy (FT). Advanced cases may benefit from video-assisted thoracoscopic debridement (VATD), with imaging guiding treatment decisions.
Area of Science:
- Pediatric Pulmonology
- Thoracic Surgery
- Medical Imaging
Background:
- Pediatric empyema requires effective and cost-efficient treatment strategies.
- Current therapeutic options include thoracostomy tube drainage (TTD) with or without fibrinolytic therapy (FT), and video-assisted thoracoscopic debridement (VATD).
Purpose of the Study:
- To evaluate the efficacy and cost-effectiveness of different treatment protocols for pediatric empyema based on radiographic appearance.
- To determine the optimal timing and modality for intervention in pediatric empyema cases.
Main Methods:
- Retrospective case series conducted at a tertiary referral center.
- Analysis of 31 children treated between 1995 and 1999.
- Comparison of outcomes and costs for TTD (with or without FT) versus VATD.
Main Results:
- TTD with or without FT was successful in most pediatric empyema cases (85.2%).
- Salvage VATD was required in 14.8% of TTD cases, with higher associated costs and length of stay.
- Primary VATD was performed in 12.9% of cases, demonstrating shorter hospital stays and lower overall charges compared to salvage VATD.
- Complications were minimal, with no significant adverse events related to urokinase therapy.
Conclusions:
- TTD with or without FT is a safe and effective first-line treatment for early-stage pediatric empyema.
- Primary VATD is recommended for children with advanced disease.
- An algorithmic approach utilizing imaging (CT or ultrasonography) can improve prediction of treatment failure and optimize cost-effectiveness.
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