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Computation of writhe in modeling of supercoiled DNA
1Division Biophysics of Macromolecules, German Cancer Research Center, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.
Biopolymers
|August 10, 2000
Abstract:
We describe four previously unpublished methods allowing the computation of the writhe for a supercoiled DNA molecule modeled by a polymer chain consisting of straight segments. These methods are compared with each other in terms of computational efficiency and the scope of their applicability is discussed.