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Updated: Aug 15, 2026
10:19
Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
Published on: November 10, 2014
[Thyroid cancer. Report of 85 cases]
P Piraino1, A Sepúlveda, R Lillo
1Departamento de Medicina, Hospital Clínico de la Universidad de Chile. ppiraino@rdc.cl
Revista Medica De Chile
|August 30, 2000
Summary
Thyroid cancer is more common in women and often presents as solid nodules with calcifications. Differentiated cancers, particularly papillary thyroid cancer, are most frequent, with accurate diagnosis via pathological studies.
Area of Science:
- Endocrinology
- Oncology
- Pathology
Background:
- Thyroid cancer is the most common endocrine malignancy.
- Accurate diagnosis and treatment are crucial.
- This study focuses on pathological findings of surgical thyroid cancer specimens.
Purpose of the Study:
- To analyze a cohort of thyroid cancer patients.
- To correlate clinical, imaging, and cytological findings with definitive pathological diagnoses.
- To evaluate diagnostic accuracy of fine needle aspiration cytology and frozen section biopsies.
Main Methods:
- Retrospective analysis of 85 thyroid cancer patients.
- Review of clinical, ultrasonographic, cytological, and pathological data.
- Comparison of fine needle aspiration cytology and intraoperative frozen biopsy results against final pathology.
Main Results:
- Thyroid cancer predominantly affects women (68/85).
- Ultrasonography revealed solid nodules (84%) and calcifications (23.5%).
- Papillary thyroid cancer (75%) was the most common type, followed by follicular (16.5%).
- Fine needle aspiration cytology had a 9.9% false negative rate; frozen biopsy had a 10.6% false negative rate.
Conclusions:
- Thyroid cancer is more prevalent in women.
- Solid nodules with calcifications are common ultrasonographic findings.
- Differentiated thyroid cancers (papillary and follicular) are the most frequent types.
- Pathological study confirms high diagnostic sensitivity for fine needle cytology (90.1%) and frozen section (89.4%).
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