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Related Experiment Videos

[Necrotizing enterocolitis: a historical and current review].

B Kreft1, K Dalhoff, K Sack

  • 1Medizinische Klinik I, Medizinischen Universität Lübeck.

Medizinische Klinik (Munich, Germany : 1983)
|September 14, 2000
PubMed
Summary
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Enteritis necroticans, or "Darmbrand," is a severe infectious disease caused by Clostridium perfringens Type C. This review covers its historical epidemic, tropical occurrences, and current understanding of its epidemiology, pathogenesis, and treatment.

Area of Science:

  • Infectious Diseases
  • Gastroenterology
  • Microbiology

Context:

  • Enteritis necroticans (Darmbrand) was epidemic in post-WWII Northern Germany and is also a tropical cause of bloody diarrhea.
  • The disease is linked to Clostridium perfringens Type C and associated with pig feasts in Papua New Guinea.

Purpose:

  • To review the historic and current aspects of enteritis necroticans.
  • To discuss the epidemiology, pathogenesis, and treatment of this rare but fulminant disease.

Summary:

  • Enteritis necroticans is a severe infectious intestinal disease caused by Clostridium perfringens Type C.
  • Historically, it caused an epidemic in Northern Germany and is also known in tropical regions.
  • Despite its rarity, awareness of its fulminant nature is crucial.

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Impact:

  • Provides a comprehensive overview of a rare but life-threatening intestinal infection.
  • Highlights the importance of recognizing Enteritis Necroticans in both historical and contemporary contexts.
  • Informs understanding of Clostridium perfringens Type C-related diseases and their management.