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A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
Non-Wilms' renal tumors in children
1Section of Pediatric Urology, Children's Hospital of Atlanta, Georgia, USA.
The Urologic Clinics of North America
|September 14, 2000
Summary
Childhood renal tumors are rare, with Wilms' tumors comprising most cases. Other kidney cancers, including clear cell sarcoma and rhabdoid tumors, are even less common in pediatric patients.
Area of Science:
- Pediatric Oncology
- Nephrology
- Cancer Research
Background:
- Renal tumors in children are uncommon, with Wilms' tumors representing the majority.
- Non-Wilms' renal tumors constitute a small fraction of childhood cancers.
Purpose of the Study:
- To summarize the incidence and types of non-Wilms' renal tumors in childhood.
- To highlight the relative rarity of these pediatric kidney cancers.
Main Methods:
- Literature review of pediatric renal neoplasms.
- Analysis of epidemiological data on childhood kidney tumors.
Main Results:
- Wilms' tumors account for 6-7% of childhood cancer.
- Other renal tumors collectively represent less than 1% of childhood cancer.
- Common non-Wilms' tumors include clear cell sarcoma, rhabdoid tumor, renal cell carcinoma, mesoblastic nephroma, and multilocular cystic nephroma.
Conclusions:
- Non-Wilms' renal tumors are infrequent in pediatric populations.
- Understanding the spectrum of these rare tumors is crucial for diagnosis and treatment.
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