Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vibrio cholerae O139 Bengal: a descriptive study.

M S Hossain1, M A Salam, G H Rabbani

  • 1ICDDR,B: Centre for Health and Population Research, Dhaka, Bangladesh. shossain@icddrb.org

Journal of Health, Population, and Nutrition
|October 3, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect on Serum Calcium in Patients with Type 2 Diabetes Mellitus.

Mymensingh medical journal : MMJ·2026
Same author

Association of Iron Deficiency Anemia with Migraine: A Case-Control Study.

Mymensingh medical journal : MMJ·2026
Same author

Relation between Cardiometabolic Risk Factors and Renal Function among Elderly Population.

Mymensingh medical journal : MMJ·2026
Same author

Effect of Nd: YAG Laser Capsulotomy Size on Visual Acuity and Posterior Segment Outcomes: A 6-Months Follow-Up Study.

Mymensingh medical journal : MMJ·2026
Same author

Association of Depressive Symptoms with Glycemic Control and Diabetic Complications in Patients with Type 2 Diabetes Mellitus: A Facility-Based Cross-Sectional Study in Bangladesh.

Mymensingh medical journal : MMJ·2025
Same author

Association between Duration of Visual Symptoms and Early Postoperative Visual Outcome Following Pituitary Macroadenoma Surgery.

Mymensingh medical journal : MMJ·2025

Cholera caused by Vibrio cholerae O139 Bengal presents similar clinical and laboratory features to conventional cholera. Management strategies for this O139 strain are comparable to those used for Vibrio cholerae O1 infections.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Clinical Medicine

Background:

  • Cholera remains a significant public health concern globally.
  • Emergence of new strains like Vibrio cholerae O139 Bengal necessitates understanding their unique characteristics.
  • Previous studies highlight the clinical and epidemiological impact of Vibrio cholerae O1.

Purpose of the Study:

  • To prospectively investigate the clinical and laboratory features of cholera caused by Vibrio cholerae O139 Bengal.
  • To delineate the clinical course and management of patients infected with this specific strain.
  • To compare the characteristics of O139 cholera with conventional O1 cholera.

Main Methods:

  • Prospective study design involving 22 adult male patients.
  • Stool culture-proven Vibrio cholerae O139 infection.

Related Experiment Videos

  • Laboratory analysis of serum and stool electrolytes (sodium, potassium, chloride, bicarbonate).
  • Assessment of fecal leukocytes and antimicrobial susceptibility testing of isolates.
  • Quantification of stool volume and fluid requirements (intravenous and oral rehydration).
  • Monitoring of diarrhea duration and pathogen excretion period.

    • Main Results:

    • Patients exhibited mean serum electrolyte concentrations: Na 134 ± 3, K 4 ± 1, Cl 102 ± 4, HCO3 13 ± 4 mmol/L.
    • Stool electrolyte concentrations were: Na 120 ± 24, K 18 ± 6, Cl 93 ± 16, HCO3 37 ± 9 mmol/L.
    • Seventeen patients (7.8%) had fecal leukocytes (11-50/HPF).
    • All O139 isolates were susceptible to tetracycline, erythromycin, and ciprofloxacin; 92% to furazolidine; 5% to trimethoprim-sulfamethoxazole.
    • Median stool volume in 24 hours was 9 L (IQR 5-12 L); total stool volume was 16 L (IQR 9-24 L).
    • Median fluid requirements: 9 L (IQR 6-18 L) IV, 14 L (IQR 9-20 L) oral.
    • Median diarrhea duration was 80 hours (IQR 48-104 hours); median V. cholerae O139 excretion was 5 days (IQR 3-6 days).

    Conclusions:

    • Clinical and laboratory findings in Vibrio cholerae O139 Bengal cholera are highly similar to conventional Vibrio cholerae O1 cholera.
    • Case management, including fluid resuscitation and antimicrobial therapy, should follow established guidelines for cholera.
    • Vibrio cholerae O139 Bengal demonstrates a distinct antimicrobial susceptibility profile, with high susceptibility to tetracycline, erythromycin, and ciprofloxacin.