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Updated: Aug 8, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
[Unifocal Langerhans cell granulomatosis in a young woman]
C Gómez Sánchez-Biezma1, E Pintor Holguín, M J Téllez Molina
1Servicio de Medicina Interna III, Hospital Clínico Universitario de San Carlos, Madrid.
Abstract:
We report a 24-years-old woman who presented with thoracic pain after coughing. Physical exam revealed no abnormalities except pain after pressing under blade-bone area. A rib radiography and CT of the thorax showed a lonely osteolytic lesion inside eleventh left costal arch without affecting others tissues. There were no more osteolytic lesions at other levels and the histopathological study of a resection-biopsy of the lesion was diagnosed as Langerhans' cell granulomatosis. This is an uncommon disease which diagnosis can only be made through histopathological study of suspected lesions.