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[Transitional cell carcinoma of urachus: a case report]
Hinyokika Kiyo. Acta Urologica Japonica
|December 7, 2000
Summary
This study details a rare case of transitional cell carcinoma originating in the urachus and extending to the ureter in a 72-year-old man. The findings highlight the importance of investigating unusual bladder tumors for urachal and ureteral involvement.
Area of Science:
- Urology
- Oncology
- Pathology
Background:
- Transitional cell carcinoma (TCC) is the most common bladder cancer.
- Urachal remnants can rarely develop malignancies, often presenting atypically.
- A history of bladder cancer increases surveillance needs.
Observation:
- A 72-year-old male with prior bladder cancer presented with a papillary tumor at the right ureteral orifice.
- Initial cystoscopy revealed no surface bladder lesions but a submucosal eminence at the bladder dome.
- Magnetic resonance imaging (MRI) identified a 2 cm extravesical tumor at the urachus.
Findings:
- Pathological examination confirmed transitional cell carcinoma in both the urachus and the right ureter.
- The urachal tumor infiltrated the bladder dome's muscularis layer, despite intact surface mucosa.
- The urachal cavity was found to be completely isolated from the bladder.
Implications:
- This case underscores the potential for urachal tumors to present with or coexist with ureteral malignancies.
- Complete resection and pathological assessment are crucial for accurate diagnosis and staging of urachal and associated cancers.
- Enhanced surveillance and diagnostic modalities like MRI are vital for detecting rare urachal malignancies.