Luteal phase deficiencies in peripubertal rhesus monkeys: mechanistic considerations

Short luteal phases in peripubertal monkeys were identified by abbreviated progesterone secretion. Evaluation of the hormonal profiles for LH, FSH, and estradiol revealed that depressed serum concentrations of FSH during the follicular phase and LH and estradiol during the luteal phase were associated with luteal defects. In addition, morphological differences in the corpora lutea of short and normal luteal phases were identified. A mechanism is presented whereby inadequate follicular phase FSH secretion results in abbreviated luteal function.