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Relationship between rheological and hemodynamic changes in rats with crush syndrome
G A Chernysheva1, M B Plotnikov, V I Smol'yakova
1Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences, Tomsk, Russia.
Bulletin of Experimental Biology and Medicine
|February 22, 2001
Abstract:
Narcotized rats with crush syndrome develop severe syndrome of increased blood viscosity. A strict correlation was found between changes in blood viscosity at different shear rates and total peripheral vascular resistance. The severity of central hemodynamic and hemorheological disturbances was different in rats with different reaction of total peripheral vascular resistance to injury accompanied by shock.