[A study on DPOAE in patients with diabetes mellitus]

In present experiment we tested DPOAE in 19 patients with diabetes mellitus and compared with control subjects. Results showed that DPOAE (f2 above 3 kHz) disappeared in 2 patients (3 ears) indicating cochlear lesion, both of DPOAE contralateral suppressive effects and selective attention effects significantly reduced in 4 patients (7 ears), and reversed in 3 patients (6 ears) indicating disorders existing in cortex topdown and efferent of MOCS. It was suggested that tests of DPOAE and suppression (induced by CAS and selective attention) may be useful for making early diagnosis of cochlear-pathy and auditory efferent disorders (cortex and MOCS) before retinalpathy happened. This study on DPOAE provided important evidence for early diagnosis and early treatment of diabetic complications.