[Light and electron microscopy studies on malformed spermatids in 2 cases of teratozoospermia]

Two distinct types of spermatid malformation resulting in teratozoospermia are demonstrated in two patients by means of light and electron microscopy. In one case of male infertility, a disturbance of the process of nuclear condensation was found which yielded pathological spermatozoa with triangular or hookshaped heads. In another case of infertility, exclusively polynucleated spermatids were detected. Atypical acrosomes, showing widely varying structural features, interconnect the nuclei. The significant of these malformations for the understanding of the differentiation of spermatids is discussed.