Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cocaine-induced persistent dyskinesias.

W J Weiner1, A Rabinstein, B Levin

  • 1Department of Neurology, University of Maryland School of Medicine, Baltimore 21201, USA.

Neurology
|April 11, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Antechodynamics and Antechokinetics: Dynamics and Kinetics of Antibiotic Resistance Biomolecules.

Biomolecules·2025
Same author

Simultaneous cochlear implantation and removal of acoustic neuroma: implications for hearing.

The Journal of laryngology and otology·2020
Same author

Endovascular Management of Acute Stroke in the Elderly: A Systematic Review and Meta-Analysis.

AJNR. American journal of neuroradiology·2018
Same author

Prenatal fever and autism risk.

Molecular psychiatry·2017
Same author

Smoking, alcohol and caffeine in relation to two hormonal indicators of ovarian age during the reproductive years.

Maturitas·2016
Same author

Macrochimerism in Intestinal Transplantation: Association With Lower Rejection Rates and Multivisceral Transplants, Without GVHD.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2015
Same journal

Factors Associated With Disability Improvement and Worsening Independent of Attacks in Patients With AQP4-IgG+ NMOSD and MOGAD: A Multicenter Cohort Study.

Neurology·2026
Same journal

Cost-Effectiveness of Intracranial Aneurysm Screening: A Systematic Review.

Neurology·2026
Same journal

Rare Eating Epilepsy: Co-Occurrence of Focal Cortical Dysplasia and Gray Matter Heterotopia.

Neurology·2026
Same journal

Spatiotemporal Associations Between Cortical Microinfarcts and Cortical Superficial Siderosis in Cerebral Amyloid Angiopathy.

Neurology·2026
Same journal

Blood-Brain Barrier Disruption Before Interhospital Transfer for Thrombectomy and Clinical Outcome.

Neurology·2026
Same journal

At Death's Door: Cytosolic Dopamine in Patients With Parkinson Disease.

Neurology·2026
See all related articles

This case study details a woman with cocaine abuse who developed persistent choreodystonic dyskinesias and obsessive-compulsive disorder. These neurological and behavioral symptoms continued even after 20 months of abstinence from cocaine.

Area of Science:

  • Neurology
  • Neuroscience
  • Psychiatry

Background:

  • Cocaine abuse is a significant public health concern associated with various neurological and psychiatric complications.
  • Understanding the long-term effects of substance abuse on brain function is crucial for effective treatment strategies.

Observation:

  • A 34-year-old woman with a history of extensive cocaine abuse presented with new-onset choreodystonic dyskinesias.
  • She also developed a significant obsessive-compulsive behavior disorder.

Findings:

  • The patient's abnormal involuntary movements (dyskinesias) and obsessive-compulsive behaviors persisted.
  • These symptoms remained evident even after a prolonged 20-month period of confirmed cocaine abstinence.

Implications:

Related Experiment Videos

  • This case highlights the potential for persistent, long-term neurological and behavioral sequelae following chronic cocaine abuse.
  • It suggests that cocaine-induced movement disorders and psychiatric conditions may not be fully reversible with abstinence alone.
  • Further research is warranted to explore the underlying neurobiological mechanisms and potential therapeutic interventions for such persistent conditions.