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Updated: Aug 15, 2026
Surgical Technique for the Implantation of Tissue Engineered Vascular Grafts and Subsequent In Vivo Monitoring
Published on: April 3, 2015
Tissue engineering of vascular bypass grafts: role of endothelial cell extraction
A Tiwari1, H J Salacinski, G Hamilton
1Vascular Haemodynamic Unit, University Department of Surgery, Royal Free and University College Medical School, Unuiversity College London, The Royal Free Hospital, London NW3 2QG, U.K.
Abstract:
Surgical treatment of vascular disease has become common. The use of synthetic materials is limited to grafts larger than 5-6 mm, because of the frequency of occlusion observed with small-diameter prosthetics. An alternative would be a hybrid or tissue-engineered graft with the surface coated with a monolayer of the patients' own endothelial cells. This review examines the various techniques and technologies used to date in order to extract endothelial cells for such graft engineering.
