Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Minimizing potential resistance: the molecular view.

P Courvalin1, P Trieu-Cuot

  • 1Unité des Agents Antibactériens, Institut Pasteur, Paris, France. pcourval@pasteur.fr

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|August 29, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A penicillin- and metronidazole-resistant Clostridium botulinum strain responsible for an infant botulism case.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2016
Same author

Why is antibiotic resistance a deadly emerging disease?

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2016
Same author

Structural insights into the loss of penicillinase and the gain of ceftazidimase activities by OXA-145 β-lactamase in Pseudomonas aeruginosa.

The Journal of antimicrobial chemotherapy·2015
Same author

Epidemiology of invasive Streptococcus pyogenes infections in France in 2007.

Journal of clinical microbiology·2011
Same author

Invasive group A streptococcal infections in adults, France (2006-2010).

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2011
Same author

Invasive group B streptococcal infections in adults, France (2007-2010).

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2011
Same journal

Reconsidering ambiguous language in infectious disease consult recommendations.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Antibiotic Treatment Duration for Uncomplicated Monomicrobial Enterococcal Bloodstream Infection: A Multicenter Target Trial Emulation.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Larger Blood Volume Increases Detection of Fastidious Mycobacteria and Fungi in Blood Culture.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Anticalcitonin: Limited utility of a context-dependent biomarker demonstrated in another real-world data set.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Procalcitonin Testing in Community-Acquired Pneumonia.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Wanted: A Relevant Correlate of Protection for Dengue Vaccines.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
See all related articles

Molecular biology advances reveal antibiotic resistance mechanisms and dissemination routes. This knowledge aids in developing new drugs and strategies to combat resistant bacteria, improving human therapy and antibiotic use.

Area of Science:

  • Molecular Biology
  • Microbiology
  • Pharmacology

Background:

  • Antibiotic resistance is a growing global health threat.
  • Understanding resistance mechanisms is crucial for effective treatment.
  • Molecular biology has significantly advanced our knowledge of bacterial resistance.

Purpose of the Study:

  • To review the contributions of molecular biology to understanding and combating antibiotic resistance.
  • To highlight how molecular insights can guide practical strategies against resistant bacteria.

Main Methods:

  • Review of existing literature on molecular biology and antibiotic resistance.
  • Analysis of biochemical mechanisms of resistance.
  • Examination of genetic information dissemination pathways in bacteria.

Related Experiment Videos

Main Results:

  • Molecular biology has elucidated key resistance mechanisms and genetic transfer routes.
  • Fundamental molecular approaches have practical applications in minimizing resistance.
  • These applications include improved phenotype interpretation, enhanced therapy, prudent antibiotic use, and rational drug design.

Conclusions:

  • Molecular biology offers powerful tools to counteract the evolution of antibiotic resistance.
  • Continued molecular research is essential for developing novel drugs and strategies.
  • Integrating molecular insights into clinical practice and antibiotic stewardship is vital.