Related Experiment Video
Updated: Aug 18, 2026
Derivation of Hematopoietic Stem Cells from Murine Embryonic Stem Cells
Published on: February 25, 2007
Allogeneic stem cell transplantation for Evans syndrome
Y Oyama1, E B Papadopoulos, M Miranda
1Division of Immune Therapy and Autoimmune Diseases, Northwestern University Medical Center, Chicago, IL, USA.
Abstract:
Evans syndrome is a rare disorder characterized by combined autoimmune thrombocytopenia (ITP) and autoimmune hemolytic anemia (AIHA). Standard treatments consist of transfusions, corticosteroids, splenectomy, IVIG, anabolic steroids, vincristine, alkylating agents, or cyclosporine. In a patient with refractory disease, an allogeneic hematopoietic stem cell transplant (HSCT) resulted in complete clinical and serologic remission for more than 30 months. Allogeneic HSCT may be the only current curative therapy for Evans syndrome but may also be complicated by significant toxicities.
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