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Updated: Jul 31, 2026

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In Vivo Biosensor Tracks Non-apoptotic Caspase Activity in Drosophila
Published on: November 27, 2016
Adenosine-induced caspase activity in N1E-115 cells
S M Schier1, A P Ijzerman, G J Mulder
1Department of Toxicology and Medicinal Chemistry, Leiden/Amsterdam Center for Drug Research, Leiden University, The Netherlands.
Advances in Experimental Medicine and Biology
|January 11, 2002
Summary
No abstract available in PubMed .
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Caspase, a family of cysteine proteases, serve as effectors in apoptosis. The ced3 gene in C.elegans was first identified to be involved in apoptosis. This gene encodes the ced-3 caspase that is similar to the interleukin-1-beta converting enzyme or ICE in mammals. In addition to apoptosis, caspases also function in the inflammatory response. Inflammatory caspases are essential in activating pro-inflammatory cytokines that recruit immune cells and block the replication of pathogens inside cells.
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