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[Neurotrichinosis]
K Knezević1, V Turkulov, G Canak
1Klinicki centar, Novi Sad.
Medicinski Pregled
|March 6, 2002
Summary
Neurotrichinellosis, a rare central nervous system complication of Trichinella spiralis infection, can present with flu-like symptoms and neurological deficits. Prompt diagnosis and treatment with mebendazole and prednisolone led to a favorable outcome in a 30-year-old patient.
Area of Science:
- Neurology
- Infectious Diseases
- Parasitology
Background:
- Trichinellosis is an anthropozoonosis caused by Trichinella spiralis, a parasite that can lead to central nervous system (CNS) complications.
- Neurotrichinellosis, a rare manifestation, presents diagnostic challenges due to its polymorphous symptomatology.
Observation:
- A 30-year-old patient presented with flu-like symptoms, somnolence, disorientation, and right hemiparesis.
- Diagnosis was confirmed by indirect immunofluorescence test showing elevated Trichinella antibody titers.
- Cerebrospinal fluid analysis was normal, while EEG and MRI revealed moderate cerebral dysfunction and multifocal changes, respectively.
Findings:
- The patient exhibited a severe form of neurotrichinellosis with neurological deficits.
- Treatment with mebendazole and prednisolone resulted in complete recovery without sequelae.
- Central nervous system involvement occurs in 10-15% of trichinellosis cases.
Implications:
- Trichinellosis should be considered in the differential diagnosis of encephalitis, especially when accompanied by flu-like symptoms and gastrointestinal issues.
- Early recognition and treatment are crucial for favorable outcomes in neurotrichinellosis.
- This case highlights the importance of considering parasitic infections in neurological presentations.