Related Experiment Video
Updated: Aug 5, 2026

Induction of Hypoxia in Living Frog and Zebrafish Embryos
Published on: June 26, 2017
Genetic lessons from high altitude
1University of Vermont, Burlington, USA.
Abstract:
What lessons can we learn from mountain sickness or wellness that may apply to our patients? Does hypoxia affect us similarly regardless of its cause? Millions of individuals are as hypoxic from congenital or acquired heart or lung disease as healthy individuals may be at altitude. Certain adjustments enable many of such patients to lead nearly normal lives. I will compare their adjustments to those seen in the acclimatization of healthy persons to altitude. Some living organisms use strategies which enable them to tolerate a degree of hypoxia lethal to man. Are there lessons we can learn from them? In my short talk I will raise a few provocative questions, and these will lead me to discuss the relevance of basic research to the resolution of vexing human ailments. When does commercialization of research become a form of intellectual prostitution?
Related Concept Videos
Background and Environment Affect Phenotype
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
Factors Affecting Respiration
Human Genetics
The complex relationship between genetics and psychology is observable through common biological components such...
Gene-Environment Interactions
Heritability
Natural Selection and Adaptation
Beyond physical adaptations, psychological...

