Related Experiment Video
Updated: Aug 8, 2026

Cecal Ligation Puncture Procedure
Published on: May 7, 2011
[Sepsis and septic shock: a turmoil of inflammatory mediators with difficult therapeutic management]
H J Durán Giménez-Rico1, M A Aller Reyero, L Lorente Ruigómez
1Departamento de Cirugía, Facultad de Medicina, Universidad Complutense, Madrid.
Abstract:
Sepsis and septic shock continue being a topic of enormous interest for their high frequency, and for not existing a decrease in the figures of mortality in spite of the new acquired knowledges relation with their physiopathology and the advances arisen in the diverse applied treatments. The purpose of the present study is to update the present notions in the specialized literature, trying to summarize the complex existent interaction among different mediators of double character: exogenous and endogenous, and to enunciate the possible causes for those that the novel treatments applied in the sepsis continue not to be very promising.
Related Concept Videos
Blood Pressure Imbalances and Circulatory Shock
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...
Endocarditis III: Medical Management
Pericarditis III: Medical Management
Acute Pyelonephritis II: Diagnostic Studies and Management
Acute Inflammation III: Local and Systemic Effects
Bacterial Meningitis II: Pathophysiology

