[Morphogenesis and some problems of the pathogenesis of experimental Pasteurella infection in white mice]

The authors present materials on the study of the principal stages of morphogenesis of experimental pasteurellosis infection in albino mice in subcutaneous, intraperitoneal and intranasal infection. Particular attention was paid to the interrelations in the organism between the cells realizing the protective functions and the causative agent. It was established that the highly-virulent P. multocida strain was capable of intracellular reproduciton in the cells of the macrophage type. It was demonstrated that the protective course of infection was largely determined by its high rate of reproduction and its capacity to paralyze the protective function of leukocytes.