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Mechanisms of extraribosomal protein biosynthesis in eukaryotes
A V Mal'tsev1, A A Firsova, E V Il'ina
1Institute of Physical and Chemical Medicine, Russian Ministry of Health, Moscow.
Bulletin of Experimental Biology and Medicine
|July 19, 2002
Abstract:
The appearance of newly synthesized proteins in the total protein fraction of a cell-free protein-synthesizing system not containing ribosomes and mRNA and enriched with polyenzyme complexes of aminoacyl-tRNA synthetases and corresponding proteins is proved experimentally. For modeling of extraribosomal protein biosynthesis we proposed a molecular polyenzyme mechanism of protein biosynthesis on a protein matrix.