Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Temporal structure in neuronal activity during working memory in macaque parietal cortex.

Bijan Pesaran1, John S Pezaris, Maneesh Sahani

  • 1Division of Physics, Mathematics & Astronomy, California Institute of Technology, Pasadena, California 91125, USA.

Nature Neuroscience
|July 23, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A wireless subdural-contained brain-computer interface with 65,536 electrodes and 1,024 channels.

Nature electronics·2026
Same author

Duration-modulated neural population dynamics in humans during BMI controls.

Communications biology·2026
Same author

Microscale organization and separability of upper extremity representations in the human motor homunculus.

Research square·2026
Same author

The Compositional Encoding of Hand-Eye Coordinated Movements for Single Neurons in the Posterior Parietal Cortex.

bioRxiv : the preprint server for biology·2026
Same author

Thalamus: a real-time system for synchronized, closed-loop multimodal behavioral and electrophysiological data capture.

Communications engineering·2026
Same author

Real-time brain-computer interface control of walking exoskeleton with bilateral sensory feedback.

Brain stimulation·2026
Same journal

Neural timescales from a computational perspective.

Nature neuroscience·2026
Same journal

Author Correction: Spinal cord Tau pathology induces tactile deficits and cognitive impairment in Alzheimer's disease via dysregulation of CCK neurons.

Nature neuroscience·2026
Same journal

Hippocampal theta sweeps indicate goal direction during navigation.

Nature neuroscience·2026
Same journal

Just how goal-directed are hippocampal theta sweeps, anyway?

Nature neuroscience·2026
Same journal

Goal-directed hippocampal theta sweeps during memory-guided navigation.

Nature neuroscience·2026
Same journal

Connectomic evidence that ordered activity drives neuromuscular network formation.

Nature neuroscience·2026
See all related articles

Gamma band oscillations in parietal cortex support working memory by maintaining neural activity. This finding advances understanding of brain function and potential neural prosthetics.

Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Systems Neuroscience

Background:

  • Working memory relies on sustained neural activity in cortical structures.
  • The mechanisms for maintaining this elevated activity are not fully understood.

Purpose of the Study:

  • To investigate the role of reverberating activity in maintaining working memory.
  • To analyze the temporal structure of neural activity in the parietal cortex during a memory task.

Main Methods:

  • Studied local field potential (LFP) and spiking activity in area LIP of awake macaques.
  • Utilized spectral analysis to examine gamma band power and coherence.
  • Performed single-trial decoding of LFP activity.

Main Results:

Related Experiment Videos

  • Elevated, spatially tuned gamma band power (25-90 Hz) was observed in LFP and spiking activity during the memory period.
  • Gamma band activity showed coherence between LFP and spiking, unlike lower frequencies.
  • LFP activity accurately predicted movement time and discriminated directional information, comparable to spike rates.

Conclusions:

  • Sustained gamma band oscillations in the parietal cortex play a crucial role in maintaining working memory.
  • LFP activity in the parietal cortex holds significant information for decoding cognitive states and predicting behavior.
  • These findings could inform the development of advanced cortical neural prostheses.