Surgical techniques of melanoma and sentinel node biopsy

The adequacy of surgical treatment of melanoma patients is the most important milestone in the natural history of the disease, once the diagnosis has been confirmed. Surgery plays a fundamental role in the initial stages of the disease, ie, to remove the primary lesion and to excise accurately the locoregional metastases. On the contrary, the impact of a surgical indication to treat distant metastases has never been confirmed in a prospective study; thus, there are no standard guidelines and it represents a decision to be discussed with each individual patient.