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Centrifugal blood pumps for various clinical needs
Seiji Ichikawa1, Yukihiko Nosé
1Michael E DeBakey Department of Surgery, Artificial Organ Research Laboratory, Baylor College of Medicine, Houston, Texas 77030, USA.
Artificial Organs
|October 31, 2002
Summary
Centrifugal blood pumps have advanced significantly, with devices like the Nikkiso pump for cardiopulmonary bypass and NEDO-developed pumps for ventricular assistance showing clinical promise. Ongoing development aims for permanently implantable biventricular assist systems.
Area of Science:
- Biomedical Engineering
- Medical Devices
- Cardiovascular Technology
Background:
- Over the last decade, diverse blood pump technologies have emerged to meet varied clinical demands.
- Centrifugal blood pumps are increasingly utilized in critical care and circulatory support.
Purpose of the Study:
- To review the historical development and current status of centrifugal blood pumps.
- To highlight advancements in pumps for cardiopulmonary bypass, short-term assistance, and long-term ventricular support.
Main Methods:
- Review of centrifugal blood pump development strategies.
- Analysis of clinical applications and experimental data for various pump designs.
Main Results:
- The Nikkiso centrifugal pump is widely used in Japanese cardiopulmonary bypass procedures (>20%).
- The Kyocera C1E3 Gryo pump supports extracorporeal membrane oxygenation for up to 28 days without thrombosis.
- NEDO-funded centrifugal pumps demonstrate safety and durability for left ventricular assistance and are adaptable for biventricular support.
Conclusions:
- Centrifugal blood pump technology has evolved for diverse clinical applications, from bypass to long-term mechanical circulatory support.
- Ongoing research focuses on developing permanently implantable biventricular assist devices, building on successful left ventricular assist device designs.